Labcorp valproic acid

Valproic acid is indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types which include absence seizures. Simple absence is defined as very brief clouding of the sensorium or loss of consciousness

Generic Name Valproic acid DrugBank Accession Number DB00313 Background. Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. 26 It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery …PTH is an 84-amino-acid peptide hormone which is responsible for the regulation of serum calcium levels within a narrow range. PTH is secreted in response to decrease in serum calcium levels by increasing the renal reabsorption of calcium and lowering reabsorption of phosphorus. The measurement of PTH is a very useful tool in the differential ...Exercise and the Glycogen-Lactic Acid System - When you exercise, you're using your muscles to create motion. The body has an incredibly complex set of processes to meet the demand...Descriptions. Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. This medicine is available only with your ...A six-part differential reported in some lab locations includes IG % and IG absolute counts. IG (immature granulocytes) includes metamyelocytes and myelocytes. It does not include bands or blast cells. 1,2 Promyelocytes and blasts are reported separately to denote the degree of left shift. An elevated percentage of IG has not been found to be ...Gastrointestinal disease can be caused by many agents, including bacteria, viruses and parasites. Culture for bacteria will not pick up the viruses or parasites. Tests for parasites will not detect the viruses or the bacteria. This GI profile is a multiplexed nucleic acid test intended for the simultaneous qualitative detection and ...Overview Depakote (Valproic Acid) is a drug used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Valproic acid is a prescription medication that has been proven effective in the treatment of epilepsy, chronic migraine headaches, and manic episodes associated with bipolar disorder, also known as manic depression. The …Valproic acid capsules are supplied as 250 mg off-white colored soft gelatin capsules, imprinted with “U-S 250”, packaged in bottles containing 100. Valproic acid capsules should not be administered to patients with hepatic disease or significant hepatic dysfunction [see Warnings and Precautions (5.1)].

Acid-fast stain of gastric aspirate has a sensitivity of 30% and provides a useful clinical diagnosis if positive. 6. Urine: Positive acid-fast stained smears with low numbers of organisms are not diagnostic, because of the presence of Mycobacterium smegmatis in genital secretions of normal patients.Valproate (valproic acid; divalproex sodium, a compound containing sodium valproate and valproic acid) controls absence, myoclonic, and tonic-clonic seizures in generalized, idiopathic, and symptomatic epilepsy. It is most useful in typical absence seizures. Valproate is as effective as ethosuximide in patients with absence seizures alone and ...Valproic Acid (Depakote)(R),S. 01. ug/mL 50-100. Detection Limit = 4. <4 indicates None Detected Toxicity may occur at levels of 100-500. Measurements of free unbound valproic acid may improve the assess- ment of clinical response. Disclaimer. The Previous Result is listed for the most recent test performed by Labcorp in the past 3 years where ...Uric Acid Serum 5d PMHG Valproic Acid Serum 6d PMHG LAVENDER – EDTA Test Name Alt Spec Add-on Site A1C None 7d P BNP None 7h M CBC None 48h PMHG Hematocrit None 48h PMHG Hemoglobin None 48h PMHG Retic None 48h PMHG ESR None 24h PMHG LIGHT BLUE – SODIUM CITRATE Test Name Alt Spec Add-on Site … Ethosuximide is well absorbed orally, and the peak plasma concentration occurs in one to four hours. It is minimally bound to plasma protein and eliminated primarily via hepatic metabolism with 10% to 20% of the administered dose excreted unchanged in the urine. The half-life is variable but averages 52 to 56 hours in adults and 32 to 41 hours ... Valproic Acid, Serum or Plasma . 716944 . Lamotrigine, Serum or Plasma . 007915 . Zonisamide, Serum or Plasma . 702690: Cannabidiol (CBD), MS, Serum or Plasma : ... Labcorp has a full suite of metabolic and biochemical genetic testing to help evaluate and monitor epilepsy patients, such as creatine, neopterin/tetrahydrobiopterin and ...Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches, and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites with Valproic Acid, can increase the concentration of Valproic Acid.Descriptions. Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. This medicine is available only with your ...

(Valproic Acid) What is Depakote / Valproic Acid? Depakote is an anti-epileptic drug that has been used to treat patients with epilepsy since 1983. It is helpful in the treatment of Partial Seizures, Absence Seizures and Generalized Tonic-Clonic Seizures. Starting the Medicine:Incidence not known. Breast enlargement. changes in hair color or texture. discoloration of the fingernails or toenails. increased hair growth, especially on the face. unexpected or excess milk flow from the breasts. Other side effects not listed may also occur in some patients.Use of valproate in pregnancy is contra-indicated for migraine prophylaxis [unlicensed] and bipolar disorder; it must only be considered for epilepsy if there is no suitable alternative treatment (see Pregnancy ). Women and girls (and their carers) must be fully informed of the risks and the need to avoid exposure to valproate medicines in ...Labcorp getting details for Valproic Acid, Free, Serum button Polar Skip to main main. Close Menu. Logins. Individuals & Patients. Find a Lab View Test Results Pay a ...

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Incidence not known. Breast enlargement. changes in hair color or texture. discoloration of the fingernails or toenails. increased hair growth, especially on the face. unexpected or excess milk flow from the breasts. Other side effects not listed may also occur in some patients.Z13.228 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2024 edition of ICD-10-CM Z13.228 became effective on October 1, 2023. This is the American ICD-10-CM version of Z13.228 - other international versions of ICD-10 Z13.228 may differ.Depakene (Valproic Acid) and Depakote (Divalproex Sodium) are closely-related drugs used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Useful for optimizing drug dosage and assessing toxicity. Notes: Also known as Depakene: CPT Code(s) 80164: Lab Section: Chemistry(Valproic Acid) What is Depakote / Valproic Acid? Depakote is an anti-epileptic drug that has been used to treat patients with epilepsy since 1983. It is helpful in the treatment of Partial Seizures, Absence Seizures and Generalized Tonic-Clonic Seizures. Starting the Medicine:

Labcorp Patient™ is your partner in managing your health. Our easy and secure Labcorp patient account allows you to get lab results, track your health history, manage appointments and pay bills—all in one place. Thinking about growing your family? Meet the Ovia apps. Get daily, personalized family health support and resources to guide you ... When it comes to scheduling medical appointments, the process can often be time-consuming and stressful. Fortunately, LabCorp makes it easy to schedule your appointment quickly and...VALPROIC ACID and VALPROIC ACID ORAL SOLUTION (valproic acid) is indicated for: • use as sole or adjunctive therapy in the treatment of simple or complex absence …Clinical Significance: Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites with valproic acid can increase the concentration of valproic acid. Therapeutic …VALPROIC ACID and VALPROIC ACID ORAL SOLUTION (valproic acid) is indicated for: • use as sole or adjunctive therapy in the treatment of simple or complex absence …LabCorp test details for Valproic Acid, serum or plasmaValproate (valproic acid; divalproex sodium, a compound containing sodium valproate and valproic acid) controls absence, myoclonic, and tonic-clonic seizures in generalized, …

Valproic Acid 007260 Microbiology / Cultures Urine Culture, Routine 008847 Stool Culture† 008144 Sputum Culture† 180810 Wound Anaerobic Culture† 183111 Blood Culture† 008300 Random, Trough, and Peak Drug Monitoring Amikacin, Peak 007204 Amikacin, Trough 007205 Amikacin, Random 007203 Gentamicin, Peak 007162 Gentamicin, Trough 007163 ...

0099310. Valproic Acid, Free and Total. VPA-F. Choose the Right Test. ARUP Consult® assists with test selection and interpretation. Therapeutic Drug Monitoring - TDM. Go to …Siro 250mg acid valproic/ 5 ml, dưới dạng muối natri, lọ 50 ml. Nang cứng chứa các hạt bao semisodium valproate ứng với 125mg acid valproic. Viên giải phóng chậm semisodium valproat ứng với 125 mg, 250 mg hoặc 500 mg acid valproic. Mã ATC. N03AG01. N - Hệ thần kinh; N03 - Thuốc chống động kinhThe patient with high cholesterol (>240 mg/dL) should have a lipid panel. Patients with cholesterol levels between 200−240 mg/dL plus two other coronary heart disease risk factors should also have a lipid panel. 1 In addition to application in screening programs for evaluation of risk factors for coronary arterial disease, lipid profiling may ...Valproic Acid Free Level (SENDOUT) Performed. Performed by LabCorp, test code 070789. ... Performed by LabCorp, test code 070789. Reported. Report available: 2-4 days.Oct 1, 2023 · GENERAL INFORMATION. Expected TAT. 4-6 Days. Clinical Use. Depakene (Valproic Acid) and Depakote (Divalproex Sodium) are closely-related drugs used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Performing Labcorp Test Code. 706499. CPT Code (s) 80164, 80165. Valproic acid concentration reported in ug/mL. Logistics. Test Indications: Valproic acid is used for treatment of seizures. Valproic acid may be used ...4086-5. 0099309. Valproic Acid, Percent Free. 32283-4. 0099791. Valproic Acid, Free. 4087-3. * Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.MMA is a four-carbon molecule that is a product of the metabolic break-down of valine, isoleucine, and propionic acid. 1 Vitamin B12 is a critical cofactor for the conversion of MMA to succinate. 1 As a result, vitamin B 12 deficiency causes an accumulation of MMA in the serum. 1 MMA concentrations will often become elevated in the early stages of vitamin B …

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Exercise and the Glycogen-Lactic Acid System - When you exercise, you're using your muscles to create motion. The body has an incredibly complex set of processes to meet the demand... Additional Information. MMA is a four-carbon molecule that is a product of the metabolic break-down of valine, isoleucine, and propionic acid. 1 Vitamin B12 is a critical cofactor for the conversion of MMA to succinate. 1 As a result, vitamin B 12 deficiency causes an accumulation of MMA in the serum. 1 MMA concentrations will often become ... LabCorp test: 007260 ( LabCorp ) Components: Valproic Acid (Depakote) (R),S. Valproic Acid, Serum or Plasma test cost is between $77.00 and $140.00. None Valproic Acid, … Valproic acid is an inhibitor of HDAC1 with IC50 value of 0.4mM [1]. Valproic acid (VPA) is a branched short-chain fatty acid. It is previously synthesized and used as an inert solvent of organic compounds. VPA is then found to have ability in preventing pentylenetetrazol-induced convulsions in rodents. It is used as an antiepileptic drug via ... Additional Information. MMA is a four-carbon molecule that is a product of the metabolic break-down of valine, isoleucine, and propionic acid. 1 Vitamin B12 is a critical cofactor for the conversion of MMA to succinate. 1 As a result, vitamin B 12 deficiency causes an accumulation of MMA in the serum. 1 MMA concentrations will often become ...Background: Therapeutic drug monitoring (TDM) is recommended during valproic acid (VPA) use, and total serum concentration has been widely adopted. However, the free form of VPA is responsible for its pharmacologic and toxic effects, and the total and free concentrations are highly discordant because of VPA's highly protein bound and …There are several laboratory tests which can be done to confirm a diagnosis of cholestasis of pregnancy, including bile acids. Maternal blood levels of bile salts are often at least three times the normal level in ICP; however, the levels may be 10 to 100 times normal. Blood tests can also reveal increased levels of other liver enzymes that ...... ACID PHOSPHATASE, 96.00. 903, 792503, LB ACID PHOSPHATASE - PROSTATIC, 94.00. 904, 792504, LR ACTH ADRENOCORTICOTROPIC H. 304.00. 905, 792505, LB ACTIVATE ...Since valproic acid is highly bound, drugs that compete for protein binding sites can increase the amount of free valproic acid (biologically active protein); these include dicumarol, high dose salicylates, and phenylbutazone. If toxicity is suspected, a free valproic acid level should be obtained. ... LabCorp. CPT: 80165. PDM: 5400266. Result ...Descriptions. Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. This medicine is available only with your ... ….

Labcorp Test Number: 007260 Test Details: Valproic Acid (Depakote)(R), Serum measures the levels of valproic acid in the blood, aiding in the therapeutic drug monitoring of individuals taking Depakote. Specimen Type: Serum or plasma Fasting: Fasting may not be required. Follow specific instructions from your healthcare provider.Test ID: VALP CPT code: 80164 LOINC: 4086-5 Specimen Type: red or green nongel Frequency: Setup: Daily; TAT 24 hrs Instructions: 1.0mL serum from Red nongel tube.Alt/ plasma from green top tube.VALPROIC ACID (for example, Depakote ER®, Depakene®, Stavzor®) Obtain baseline complete blood cell counts with differential (CBC with diff); liver function tests, and pregnancy test for females. Monitor Depakote levels, liver function tests, and CBC with diff every 3-6 months. Monitor for development of polycystic ovary disease in females. Based …Labcorp test details for Ferritin. Ferritin is found in virtually all cells of the body and serves as the cellular storage repository for iron. 2,3 Ferritin is a macromolecule with an average molecular weight of near 440 kD that varies depending on the iron content. Ferritin consists of a protein shell (apoferritin) of 24 subunits surrounding an iron core consisting of up to …Clomipramine is well absorbed orally but probably undergoes significant first-pass metabolism. Metabolism may be dose-related (capacity limited), which should be kept in mind when using large doses (eg, >150 mg/day). Due to enzyme inhibition, coadministration of valproic acid may produce elevated levels of clomipramine with resultant seizures.Labcorp test details for Valproic Caustic, Serum or Plasma 007260: Valproic Acid, Serum or Plasma | Labcorp / Provider Manual - Keystone First Community HealthChoices (CHC) Skip to main contentGENERAL INFORMATION. Expected TAT. 4-6 Days. Clinical Use. Depakene (Valproic Acid) and Depakote (Divalproex Sodium) are closely-related drugs used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Performing Labcorp Test Code. 706499. CPT Code (s) 80164, 80165.Monitoring therapy, assessing compliance, and evaluating potential toxicity while receiving valproic acid treatment Clinical Significance Valproic acid is used for treatment of simple and complex absence seizures and as combination therapy with any of the other anticonvulsants for control of generalized seizures that include absence seizures.Valproic acid (valproate, Depakote, or Depakene) is an effective medication for absence seizures, generalized tonic-clonic seizures, and partial seizures, when administered alone or in conjunction with other antiepileptic agents. The valproic acid that circulates in blood is 85% to 90% protein-bound under normal circumstances.Valproic Acid Free Level (SENDOUT) Performed. Performed by LabCorp, test code 070789. ... Performed by LabCorp, test code 070789. Reported. Report available: 2-4 days. Labcorp valproic acid, Incidence not known. Breast enlargement. changes in hair color or texture. discoloration of the fingernails or toenails. increased hair growth, especially on the face. unexpected or excess milk flow from the breasts. Other side effects not listed may also occur in some patients., Urine organic acid testing is useful in the diagnosis and monitoring of patients with inborn errors of organic acid metabolism, inborn errors of amino acid metabolism, urea cycle defects, and defects of the mitochondrial respiratory chain. ... This test was developed, and its performance characteristics determined, by LabCorp. It has not been ..., Valproic acid is a branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. It has a role as an anticonvulsant, a GABA agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, a teratogenic agent, a psychotropic drug, a neuroprotective agent and an antimanic drug., Walk-In Lab. Valproic Acid Serum Test. Covered tests: Valproic Acid, Serum or Plasma ( LabCorp ) Covered components: Valproic Acid (Depakote) (R),S. Blacklisted States: …, Labcorp test details since Valproic Acid, Serum or Fluid 007260: Valproic Acid, Serum or Plasma | Labcorp | Binary Analysis and Symbolic Execution with angr Skip to main content, Valproic Acid - Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites with valproic acid can increase the concentration of valproic acid. Therapeutic drug monitoring is …, Valproic acid (valproate, Depakote, or Depakene) is an effective medication for absence seizures, generalized tonic-clonic seizures, and partial seizures, when administered alone or in conjunction with other antiepileptic agents. The valproic acid that circulates in blood is 85% to 90% protein-bound under normal circumstances., Test ID: VALP CPT code: 80164 LOINC: 4086-5 Specimen Type: red or green nongel Frequency: Setup: Daily; TAT 24 hrs Instructions: 1.0mL serum from Red nongel tube.Alt/ plasma from green top tube. Text: Monitor therapeutic level; evaluate toxicity. Methodology: Solid Phase competitive chemiluminescent enzyme immunoassay, Total Valproic Acid: 4086-5 % Free Valproic Acid: 10548-6 % Bound Valproic Acid: 21590-5. Mayo Access Code. SHO8619. Additional Information., Walk-In Lab. Valproic Acid Serum Test. Covered tests: Valproic Acid, Serum or Plasma ( LabCorp ) Covered components: Valproic Acid (Depakote) (R),S. Blacklisted States: …, Labcorp test details since Valproic Acid, Serum or Fluid 007260: Valproic Acid, Serum or Plasma | Labcorp | Binary Analysis and Symbolic Execution with angr Skip to main content, Clinical Significance. Valproic Acid - Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites with valproic acid can increase the concentration of valproic acid. , Valproic acid is an inhibitor of HDAC1 with IC50 value of 0.4mM [1]. Valproic acid (VPA) is a branched short-chain fatty acid. It is previously synthesized and used as an inert solvent of organic compounds. VPA is then found to have ability in preventing pentylenetetrazol-induced convulsions in rodents. It is used as an antiepileptic drug via ... , Labcorp test details for Valproic Acid, Serum instead Plasma 007260: Valproic Acid, Serum or Plasma | Labcorp / Provider Manual - Keystone First Community HealthChoices (CHC) Bounce to main content, Additional Information. MMA is a four-carbon molecule that is a product of the metabolic break-down of valine, isoleucine, and propionic acid. 1 Vitamin B12 is a critical cofactor for the conversion of MMA to succinate. 1 As a result, vitamin B 12 deficiency causes an accumulation of MMA in the serum. 1 MMA concentrations will often become ..., Labcorp Patient™ is your partner in managing your health. Our easy and secure Labcorp patient account allows you to get lab results, track your health history, manage appointments and pay bills—all in one place. Thinking about growing your family? Meet the Ovia apps. Get daily, personalized family health support and resources to guide you ... , By using AccuDraw ® you understand that the tool provides guidance on the optimal draw for an adult patient of normal weight, on the day such guidance is issued. Specific instructions regarding the collection, handling, or shipping of specimens may vary from day-to-day, and should only be used on the day provided., Labcorp test details by Valproic Acerbic, Serum or Plasma 007260: Valproic Acid, Serum or Plasma | Labcorp | Provider Manual - Keystone First Community HealthChoices (CHC) Skip toward main content, Folic Acid; Free T3; Free T4; FSH; GGT; Glucose; Glucose, Whole Blood (fingerstick) ... Valproic Acid; Vitamin D, 25 OH. Coagulation. INR; Protime (PT); PTT ( ..., Clomipramine is well absorbed orally but probably undergoes significant first-pass metabolism. Metabolism may be dose-related (capacity limited), which should be kept in mind when using large doses (eg, >150 mg/day). Due to enzyme inhibition, coadministration of valproic acid may produce elevated levels of clomipramine with resultant seizures. , Drugs which compete for binding sites on albumin and which may displace phenytoin include valproic acid, acetazolamide, high doses of salicylic acid, phenylbutazone, ceftriaxone, nafcillin, and sulfamethoxazole. 7 In a clinical setting in which one of these drugs is used with phenytoin and toxicity is suspected despite normal phenytoin levels ..., Descriptions. Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. This medicine is available only with your ..., Walk-In Lab. Valproic Acid Serum Test. Covered tests: Valproic Acid, Serum or Plasma ( LabCorp ) Covered components: Valproic Acid (Depakote) (R),S. Blacklisted States: …, Step 1: Add to cart - for each panel below click "Buy Online" button. This will open in a new tab. Click "Add to Cart" button there, and then close the tab. Click Buy Online then "Add to Cart" button in the new tab. Close the tab. (Valproic Acid (Depakote) Blood Test $77.00), Oct 1, 2023 · GENERAL INFORMATION. Expected TAT. 4-6 Days. Clinical Use. Depakene (Valproic Acid) and Depakote (Divalproex Sodium) are closely-related drugs used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Performing Labcorp Test Code. 706499. CPT Code (s) 80164, 80165. , PTH is an 84-amino-acid peptide hormone which is responsible for the regulation of serum calcium levels within a narrow range. PTH is secreted in response to decrease in serum calcium levels by increasing the renal reabsorption of calcium and lowering reabsorption of phosphorus. The measurement of PTH is a very useful tool in the differential ..., Prolactin. TEST: 004465. CPT: 84146 (per specimen) Print Share Include LOINC® in print. Within 1 day. Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or ..., Use of valproate in pregnancy is contra-indicated for migraine prophylaxis [unlicensed] and bipolar disorder; it must only be considered for epilepsy if there is no suitable alternative treatment (see Pregnancy ). Women and girls (and their carers) must be fully informed of the risks and the need to avoid exposure to valproate medicines in ..., $69.00. Labcorp Test Number:007260. Test Details:Valproic Acid (Depakote)(R), Serum measures the levels of valproic acid in the blood, aiding in the therapeutic drug …, Oct 1, 2023 · GENERAL INFORMATION. Expected TAT. 4-6 Days. Clinical Use. Depakene (Valproic Acid) and Depakote (Divalproex Sodium) are closely-related drugs used for the treatment of petit mal, grand mal, mixed and akinetic-myoclonic seizures. Performing Labcorp Test Code. 706499. CPT Code (s) 80164, 80165. , None Valproic Acid, Serum or Plasma test cost minimal is in Personalabs (Valproic Acid (Depakote) Blood Test) with price $77.00. Valproic Acid, Serum or Plasma test cost max is in EconoLabs (Valproic Acid (Depakote), Serum) with price $140.00., Labcorp test details for Valproic Acid, Cellular or Plasma 007260: Valproic Acid, Serum or Plasma | Labcorp | Provider Manual - Keystone First Community HealthChoices (CHC) Skip the main site, Labcorp test details for Folate (Folic Acid) Folate assays of samples from patients receiving therapy with certain pharmaceuticals (eg, methotrexate or leucovorin), are contraindicated because of the cross-reactivity of folate-binding protein with these compounds. 1 Serum samples should not be altered with additives (biocides, …